SDS Vault Safety Data Sheet Reference

n-Hexane

CAS: 110-54-3 Category: Solvents ⚠ DANGER
Also known as: Hexane, Normal hexane, Skellysolve B

Quick Facts

CAS Number110-54-3
Signal WordDANGER
GHS Hazard Classesflammable, harmful, health hazard, environmental
NFPA RatingHealth: 1 / Flammability: 3 / Reactivity: 0
Common NamesHexane, Normal hexane, Skellysolve B
PubChem CID8058

Hazard Summary

⚠ DANGER: Petroleum-derived solvent that metabolizes to 2,5-hexanedione — a neurotoxin causing peripheral neuropathy with chronic exposure. Potentiated by MEK exposure. OSHA PEL 500 ppm; NIOSH REL 50 ppm.

GHS Hazard Pictograms

🔥 Flammable ⚠ Harmful/Irritant ❤️ Health Hazard 🌊 Environmental

Hazard Statements (H-codes)

H225 – Highly flammable liquid and vapour
H304 – May be fatal if swallowed and enters airways
H315 – Causes skin irritation
H361f – Suspected of damaging fertility
H372 – Causes damage to organs (peripheral nervous system) through prolonged or repeated exposure
H411 – Toxic to aquatic life

Precautionary Statements (P-codes)

P210 – Keep away from heat/ignition
P260 – Do not breathe vapours
P301+P310 – IF SWALLOWED: Call Poison Control; do not induce vomiting

First Aid Measures (Section 4)

👁 Eye Contact
Flush with water for 15 minutes. Seek medical attention.
🖐 Skin Contact
Wash with soap and water. Remove contaminated clothing.
🫁 Inhalation
Remove to fresh air. Chronic exposure causes "glue-sniffer neuropathy" — numbness, weakness. Report occupational exposures to physician.
🫦 Ingestion
Do NOT induce vomiting — aspiration hazard. Call Poison Control (1-800-222-1222).

Storage & Handling

🔒 Storage & Handling: Flammable storage cabinet. Bond containers when transferring. Do not co-store with MEK — combination is more neurotoxic.

PPE Requirements

Chemical goggles
Nitrile gloves
Organic vapour respirator required — OSHA PEL easily exceeded
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